Hb Grenoble	beta51(D2)Pro->Ser;
	beta52(D3)Asp->Asn

HEMATOLOGY		Not presented
ELECTROPHORESIS		Not detailed
CHROMATOGRAPHY		No information available
STRUCTURE STUDIES		Tryptic digestion of Hb X; separation of peptides by reversed phase HPLC; amino acid analysis; mass spectrometry; microsequencing
DNA ANALYSES		Not reported; presumed mutation CCT->TCT and GAT->AAT at codons 51 and 52
FUNCTION STUDIES		Not reported
STABILITY		Not reported
OCCURRENCE		Found in a French female
OTHER INFORMATION		The beta52 Asp->Asn mutation is characteristic for Hb Osu-Christiansborg

REFERENCES
1.		Lacombe, C., Promé, Blouquit, Y., Bardakdjian, J., Arous, N., Mrad, A., Promé, J-C., and Rosa, J.: Hemoglobin, 14:529, 1990.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.