Hb Sherwood Forest	beta104(G6)Arg->Thr

CONTACT		Central cavity
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X and Hb A can be separated at alkaline pH; Hb X moves faster than Hb A
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Tryptic digestion of the betaX chain; separation of peptides by fingerprinting; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation AGG->ACG at codon 104
FUNCTION STUDIES		Not reported
STABILITY		Normal
OCCURRENCE		Found in a 22-year-old female of Kashmiri Muslim origin
OTHER INFORMATION		Quantity in the heterozygote 50%

REFERENCES
1.		Ryrie, D.R., Plowman, D., and Lehmann, H.: FEBS Lett., 83:260, 1977.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.