Hb Gavello	beta47(CD6)Asp->Gly

CONTACT		External
HEMATOLOGY		Normal in the heterozygote
ELECTROPHORESIS		Hb X and Hb A separate at alkaline pH; Hb X moves as Hb S
CHROMATOGRAPHY		Not reported
STRUCTURE STUDIES		Tryptic digestion; fingerprinting; amino acid analysis; chymotryptic digestion
DNA ANALYSES		Not reported; presumed mutation GAT->GGT at codon 47
FUNCTION STUDIES		Normal
STABILITY		Normal
OCCURRENCE		Found in a 79-year-old female of North Italian origin
OTHER INFORMATION		Quantity in the heterozygote 42%

REFERENCES
1.		Marinucci, M., Mavilio, F., Tentori, L., and Alberti, R.: Hemoglobin, 1:771, 1977.

---

This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.