Hb F-Pendergrass	Agamma36(C2)Pro->Arg

ELECTROPHORESIS		Hb FX moves about like Hb S at alkaline pH
IEF		Not reported
CHROMATOGRAPHY		Hb FX separates from Hb A and Hb F by DEAE-cellulose chromatography
CHAIN SEPARATION		No data reported
STRUCTURE STUDIES		Tryptic digestion of gammaX chain; separation of peptides by reversed phase HPLC; amino acid analysis
DNA ANALYSES		Not reported; presumed mutation CCA->CGA at codon 36
NOTES		Found in a Caucasian newborn; Hb FX 6.7% of total Hb or 8.5% of total Hb F

REFERENCES
1.		Chen, S.S., Wilson, J.B., and Huisman, T.H.J.: Hemoglobin, 9:73, 1985.

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This material is from the book A Syllabus of Human Hemoglobin Variants (1996) by Titus H.J. Huisman, Marianne F.H. Carver, and Georgi D. Efremov, published by The Sickle Cell Anemia Foundation in Augusta, GA, USA. Copyright © 1996 by Titus H.J. Huisman. All rights reserved. Neither this work nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, microfilming and recording, or by any information storage and retrieval systems, without written permission.